Mass spectrometry in the integrated strategy for the structural analysis of protein variants.

doi:10.1002/bms.1200211202

Back to search

Article

Mass spectrometry in the integrated strategy for the structural analysis of protein variants.

Biological mass spectrometry - 1 Dec 1992

Wada Y

Abstract excerpt

A significant proportion of genetic disorders are caused by point mutations in proteins, and many variants of haemoglobin have been characterized by mass spectrometry. The strategy employs fast atom bombardment and/or tandem mass spectrometry of enzymatically digested peptides for elucidating the...

Topics

Amino Acid Sequence
Genetic Variation
Humans
Mass Spectrometry
Molecular Sequence Data
Point Mutation
Proteins
Spectrometry, Mass, Fast Atom Bombardment

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.