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Article

Mass spectrometry in the integrated strategy for the structural analysis of protein variants.

Biological mass spectrometry - 1 Dec 1992

Wada Y

Abstract excerpt

A significant proportion of genetic disorders are caused by point mutations in proteins, and many variants of haemoglobin have been characterized by mass spectrometry. The strategy employs fast atom bombardment and/or tandem mass spectrometry of enzymatically digested peptides for elucidating the type and position of the mutations. Electrospray ionization mass spectrometry is useful for detecting mutations in the...

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PMID: 1477107
DOI: 10.1002/bms.1200211202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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