Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Capillary zone electrophoresis and mass spectrometry for the characterization of genetic variants of human hemoglobin.

Analytical biochemistry - 1 Apr 1991

Ferranti P, Malorni A, Pucci P, Fanali S, Nardi A, Ossicini L

Abstract excerpt

This paper describes a simple and rapid analytical method for the structural identification of abnormal human hemoglobins. Globin chains obtained by precipitation of erythrocyte hemolysate in cold acetone are directly analyzed by capillary zone electrophoresis in coated capillaries without any prior treatment. The speed and the high resolving power of capillary zone electrophoresis allow fast differentiation of...

Topics

Chromatography, High Pressure Liquid
Electrophoresis
Genetic Variation
Globins
Hemoglobins
Hemoglobins, Abnormal
Humans
Peptide Mapping
Silicon Dioxide
Spectrometry, Mass, Fast Atom Bombardment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Trypsin

Source

Identifiers

PMID: 1651062
DOI: 10.1016/0003-2697(91)90143-h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1651062-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Capillary zone electrophoresis and mass spectrometry for the characterization of genetic variants of human hemoglobin.PMID 1651062Read ↗

Could capillary zone electrophoresis of tryptic peptides be used for the characterization of hemoglobin variants?Semantic proximity Read ↗

Structural characterization of hemoglobin variants using capillary electrophoresis and fast atom bombardment mass spectrometry.Semantic proximity Read ↗

Phenotype determination of hemoglobinopathies by mass spectrometry.Semantic proximity Read ↗

Advanced analytical methods for hemoglobin variants.Semantic proximity Read ↗

Rapid identification of hemoglobin variants by electrospray ionization mass spectrometry.Semantic proximity Read ↗

New results of hemoglobin variant structure determinations by fast atom bombardment mass spectrometry.Semantic proximity Read ↗

Monitoring of transferrin isoforms in biological samples by capillary electrophoresis.Semantic proximity Read ↗

Peptide mapping using thermospray LC/MS detection: rapid identification of hemoglobin variants.Semantic proximity Read ↗

A new method for fast haptoglobin phenotyping and hemoglobin binding capacity calculation based on capillary zone electrophoresis.Semantic proximity Read ↗

Identification of hemoglobin variants by top-down mass spectrometry using selected diagnostic product ions.Semantic proximity Read ↗

Determination of genetic transferrin variants in human serum by high-resolution capillary zone electrophoresis(†).Semantic proximity Read ↗

Hemoglobin variant analysis of whole blood and dried blood spots by MS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.