Article
On the use of different mass spectrometric techniques for characterization of sequence variability in genomic DNA.
Analytical and bioanalytical chemistry - 1 May 2008
Oberacher Herbert
Abstract excerpt
After completion of the human genome sequence the search for differences among individual genomes has become the centre of focus for geneticists. Two different types of polymorphism-single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs)-are major sources of genetic diversity and are of widespread use in genetic analysis. A plethora of genotyping techniques have been developed, and mass...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.