Article
Combined linkage and association tests in mx.
Behavior genetics - 1 Mar 2004
Posthuma D, de Geus E J C, Boomsma D I, Neale M C
Abstract excerpt
Statistical methods aimed at the detection of genes for quantitative traits suffer from two problems: (i) when a linkage approach is employed, relatively large sample sizes are usually required; and (ii) when an association approach is employed, effects of population stratification may blur genuine locus-trait associations. The variance components method proposed by Fulker et al. (1999) addressed both these...
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