Article
Multivariate multipoint linkage analysis of quantitative trait loci.
Behavior genetics - 1 Sept 1996
Eaves L J, Neale M C, Maes H
Abstract excerpt
Resolution of the genetic components of complex disorders may require simultaneous analysis of the contribution of individual quantitative trait loci (QTLs) to multiple variables. A likelihood approach is used to illustrate how the complexities of multivariate data may be resolved with multipoint linkage analysis. Sibling pair data were simulated from a model in which two QTLs and trait-specific polygenic effects...
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