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Article

Multivariate multipoint linkage analysis of quantitative trait loci.

Behavior genetics - 1 Sept 1996

Eaves L J, Neale M C, Maes H

Abstract excerpt

Resolution of the genetic components of complex disorders may require simultaneous analysis of the contribution of individual quantitative trait loci (QTLs) to multiple variables. A likelihood approach is used to illustrate how the complexities of multivariate data may be resolved with multipoint linkage analysis. Sibling pair data were simulated from a model in which two QTLs and trait-specific polygenic effects...

Topics

Animals
Chromosome Mapping
Factor Analysis, Statistical
Female
Genetic Linkage
Genetic Markers
Genotype
Humans
Male
Models, Genetic
Multivariate Analysis
Pedigree

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Identifiers

PMID: 8917951
DOI: 10.1007/BF02359757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8917951-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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