MQScore_SNP software for multipoint parametric linkage analysis of quantitative traits in large pedigrees.

doi:10.1111/j.1469-1809.2010.00576.x

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Article

MQScore_SNP software for multipoint parametric linkage analysis of quantitative traits in large pedigrees.

Annals of human genetics - 1 May 2010

Axenovich Tatiana I, Aulchenko Yurii S

Abstract excerpt

We describe software for multipoint parametric linkage analysis of quantitative traits using information about SNP genotypes. A mixed model of major gene and polygene inheritance is implemented in this software. Implementation of several algorithms to avoid computational underflow and decrease running time permits application of our software to the analysis of very large pedigrees collected in human genetically...

Topics

Algorithms
Body Height
Humans
Pedigree
Polymorphism, Single Nucleotide
Quantitative Trait Loci
Software

Source

Open in PubMed

Identifiers

PMID: 20529018
DOI: 10.1111/j.1469-1809.2010.00576.x

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