Article
A rapid somatic genotoxicity assay in Drosophila melanogaster using multiple mutant mutagen-sensitive (mus) strains.
Mutagenesis - 1 Nov 1992
Henderson D S, Grigliatti T A
Abstract excerpt
Mutagen-sensitive (mus) mutations in Drosophila melanogaster render developing flies hypersensitive to the lethal effects of DNA-damaging agents. In principle, multiply mutant mus strains might then serve as sensitive in vivo indicators of a wide range of mutagens and genotoxic carcinogens. As a first step to evaluate that potential we characterized interactions between mus mutations in eight double mutants...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.