DNA repair defects and other (mus)takes in Drosophila melanogaster.

doi:10.1006/meth.1999.0797

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Article

DNA repair defects and other (mus)takes in Drosophila melanogaster.

Methods (San Diego, Calif.) - 1 Jul 1999

Henderson D S

Abstract excerpt

Preservation of the structural integrity of DNA in any organism is crucial to its health and survival. Such preservation is achieved by an extraordinary cellular arsenal of damage surveillance and repair functions, many of which are now being defined at the gene and protein levels. Mutants hypersensitive to the killing effects of DNA-damaging agents have been instrumental in helping to identify DNA repair-related...

Topics

Animals
Chromosomes
Cloning, Molecular
Crosses, Genetic
DNA Mutational Analysis
DNA Repair
DNA Replication
Drosophila melanogaster
Ethyl Methanesulfonate
Genes, Insect
Insect Proteins
Phenotype
Proliferating Cell Nuclear Antigen
Promoter Regions, Genetic
Recombination, Genetic

Source

Open in PubMed

Identifiers

PMID: 10454999
DOI: 10.1006/meth.1999.0797

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