Article
The mus206 gene of Drosophila melanogaster is required in the excision repair of alkylation-induced DNA lesions.
Mutation research - 1 Aug 1997
Huang W, Smith P D
Abstract excerpt
The mus206A1 mutation, previously identified in our laboratory on the basis of increased sensitivity to methyl methanesulfonate (MMS), has undergone further analysis. Genetic recombinational mapping data localize mus206 at 2-64.8. Sex-linked recessive lethal mutation tests indicate that mus206A1 exhibits significant alkylation-induced hypermutability, compared to the wild-type Oregon R progenitor strain,...
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