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Article

Purine and pyrimidine-specific repression of the Escherichia coli carAB operon are functionally and structurally coupled.

Journal of molecular biology - 6 Feb 2004

Devroede Neel, Thia-Toong Thia-Lin, Gigot Daniel, Maes Dominique, Charlier Daniel

Abstract excerpt

Transcription of the carAB operon encoding the sole carbamoylphosphate synthetase of Escherichia coli proceeds from a tandem pair of promoters. P2, downstream, is repressed by arginine and the ArgR protein, whereas P1 is submitted to pyrimidine-specific regulation and as shown here to purine-specific control exerted by binding of the PurR protein to a PUR box sequence centered around nucleotide -128.5 with...

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Identifiers

PMID: 14741201
DOI: 10.1016/j.jmb.2003.12.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Purine and pyrimidine-specific repression of the Escherichia coli carAB operon are functionally and structurally coupled.PMID 14741201Read ↗

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