Article
pyrH-encoded UMP-kinase directly participates in pyrimidine-specific modulation of promoter activity in Escherichia coli.
Journal of molecular biology - 24 Jul 1998
Kholti A, Charlier D, Gigot D, Huysveld N, Roovers M, Glansdorff N
Abstract excerpt
The carAB operon of the enterics Escherichia coli K-12 and Salmonella typhimurium LT2, encoding the sole carbamoylphosphate synthetase (CPSase) of these organisms, is transcribed from two promoters in tandem, carP1 upstream and carP2 downstream, repressed respectively by pyrimidines and arginine....
Topics
- Adenine
- Bacterial Proteins
- DNA Methylation
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Mutation
- Nucleoside-Phosphate Kinase
- Promoter Regions, Genetic
- Pyrimidines
- Salmonella typhimurium
- Transcriptional Activation