Article
Molecular characterization of the mouse agouti locus.
Cell - 24 Dec 1992
Bultman S J, Michaud E J, Woychik R P
Abstract excerpt
The agouti (a) locus acts within the microenvironment of the hair follicle to regulate coat color pigmentation in the mouse. We have characterized a gene encoding a novel 131 amino acid protein that we propose is the one gene associated with the agouti locus. This gene is normally expressed in a manner consistent with a locus function, and, more importantly, its structure and expression are affected by a number...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Exons
- Hair Color
- Introns
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Phenotype