Article
Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage.
Genes & development - 15 Jun 1994
Michaud E J, van Vugt M J, Bultman S J, Sweet H O, Davisson M T, Woychik R P
Abstract excerpt
The agouti gene normally confers the wild-type coat color of mice. Dominant mutations at the agouti locus result in a pleiotropic syndrome that is characterized by excessive amounts of yellow pigment in the coat, obesity, a non-insulin-dependent diabetic-like condition, and the propensity to form...
Topics
- Agouti Signaling Protein
- Alleles
- Animals
- Base Sequence
- DNA, Antisense
- Gene Expression Regulation
- Gene Rearrangement
- Genes, Dominant
- Genes, Intracisternal A-Particle
- Genomic Imprinting
- Intercellular Signaling Peptides and Proteins
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL