Article
The agouti gene: turned on to yellow.
Trends in genetics : TIG - 1 Dec 1994
Siracusa L D
Abstract excerpt
The agouti locus was first identified as a result of its effects on the type and temporal deposition of coat color pigments in mammals. Many mutations at the murine agouti locus have now been found, some of which not only affect coat color, but also interfere with diverse biological processes leading to diabetes, obesity, tumor susceptibility and embryonic lethality. Correlations between the genotype and...
Topics
- Agouti Signaling Protein
- Animals
- Cloning, Molecular
- Hair Color
- Humans
- Intercellular Signaling Peptides and Proteins
- Mice
- Mutation
- Proteins