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Article

A transgenic mouse assay for agouti protein activity.

Genetics - 1 May 1995

Perry W L, Hustad C M, Swing D A, Jenkins N A, Copeland N G

Abstract excerpt

The mouse agouti gene encodes an 131 amino acid paracrine signaling molecule that instructs hair follicle melanocytes to switch from making black to yellow pigment. Expression of agouti during the middle part of the hair growth cycle in wild-type mice produces a yellow band on an otherwise black...

Topics

Actins
Agouti Signaling Protein
Animals
Base Sequence
DNA, Complementary
Female
Gene Expression Regulation
Genes
Genes, Lethal
Hair Color
Humans
Intercellular Signaling Peptides and Proteins
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred C3H

Mice, Inbred C57BL

Mice, Inbred DBA

Mice, Mutant Strains

Source

Open in PubMed Open full text

Identifiers

PMID: 7635291
DOI: 10.1093/genetics/140.1.267
PMCID: PMC1206553

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7635291-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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