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Article

A transgenic mouse assay for agouti protein activity.

Genetics - 1 May 1995

Perry W L, Hustad C M, Swing D A, Jenkins N A, Copeland N G

Abstract excerpt

The mouse agouti gene encodes an 131 amino acid paracrine signaling molecule that instructs hair follicle melanocytes to switch from making black to yellow pigment. Expression of agouti during the middle part of the hair growth cycle in wild-type mice produces a yellow band on an otherwise black hair. The ubiquitous unregulated expression of agouti in mice carrying dominant yellow alleles is associated with...

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Identifiers

PMID: 7635291
DOI: 10.1093/genetics/140.1.267
PMCID: PMC1206553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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