Article
The molecular basis for dominant yellow agouti coat color mutations.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 1994
Perry W L, Copeland N G, Jenkins N A
Abstract excerpt
Agouti expression during the middle portion of the mouse hair growth cycle induces melanocytes to synthesize yellow instead of black pigment, generating black hairs with a yellow band. Dominant agouti alleles increase the amount of yellow pigment in the coat and are associated with pleiotropic ef...
Topics
- Agouti Signaling Protein
- Alleles
- Animals
- Genes, Dominant
- Genes, Intracisternal A-Particle
- Hair Color
- Intercellular Signaling Peptides and Proteins
- Mice
- Mice, Mutant Strains
- Mutation
- Proteins