Article
Molecular and phenotypic analysis of 25 recessive, homozygous-viable alleles at the mouse agouti locus.
Genetics - 1 Feb 2002
Miltenberger Rosalynn J, Wakamatsu Kazumasa, Ito Shosuke, Woychik Richard P, Russell Liane B, Michaud Edward J
Abstract excerpt
Agouti is a paracrine-acting, transient antagonist of melanocortin 1 receptors that specifies the subapical band of yellow on otherwise black hairs of the wild-type coat. To better understand both agouti structure/function and the germline damage caused by chemicals and radiation, an allelic series of 25 recessive, homozygous-viable agouti mutations generated in specific-locus tests were characterized. Visual...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
