Article
Structure and function of <i>ASP</i>, the human homolog of the mouse <i>agouti</i> gene
1 Jan 1995
Abstract excerpt
The mouse agouti coat color gene encodes a novel paracrine signaling molecule whose pulsatile expression produces a characteristic pattern of banded pigment in individual hairs. Several spontaneous agouti alleles produce adult-onset obesity and diabetes, and have provided important single-gene animal models for alterations in energy metabolism. Utilizing linkage groups conserved between mice and humans, we have...
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