Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain.

Physiological genomics - 12 Mar 2004

Welch Carrie L, Bretschger Sara, Wen Ping-Zi, Mehrabian Margarete, Latib Nashat, Fruchart-Najib Jamila, Fruchart Jean Charles, Myrick Christy, Lusis Aldons J

Abstract excerpt

Atherosclerosis is a complex disease resulting from the interaction of multiple genes, including those causing dyslipidemia. Relatively few of the causative genes have been identified. Previously, we identified Apoa2 as a major determinant of high-density lipoprotein cholesterol (HDL-C) levels in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-II
Share to Cholesterol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, HDL

Share to Chromosomes

Share to Hypercholesterolemia

Share to Mice, Congenic

Share to Mice, Inbred NOD

Share to Multifactorial Inheritance

Source

Identifiers

PMID: 14722362
DOI: 10.1152/physiolgenomics.00124.2003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14722362-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain.PMID 14722362Read ↗

Two novel quantitative trait loci on mouse chromosomes 6 and 4 independently and synergistically regulate plasma apoB levels.Semantic proximity Read ↗

Atherosclerosis susceptibility Loci identified in an extremely atherosclerosis-resistant mouse strain.Semantic proximity Read ↗

Quantitative trait loci analysis for plasma HDL-cholesterol concentrations and atherosclerosis susceptibility between inbred mouse strains C57BL/6J and 129S1/SvImJ.Semantic proximity Read ↗

Fine mapping of Ath6, a quantitative trait locus for atherosclerosis in mice.Semantic proximity Read ↗

Polygenic Control of Carotid Atherosclerosis in a BALB/cJ × SM/J Intercross and a Combined Cross Involving Multiple Mouse Strains.Semantic proximity Read ↗

High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis.Semantic proximity Read ↗

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels.Semantic proximity Read ↗

Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci.Semantic proximity Read ↗

Genetic analysis of atherosclerosis and glucose homeostasis in an intercross between C57BL/6 and BALB/cJ apolipoprotein E-deficient mice.Semantic proximity Read ↗

Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice.Semantic proximity Read ↗

Atherosclerosis susceptibility loci identified from a strain intercross of apolipoprotein E-deficient mice via a high-density genome scan.Semantic proximity Read ↗

New quantitative trait loci for carotid atherosclerosis identified in an intercross derived from apolipoprotein E-deficient mouse strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.