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Article

High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis.

G3 (Bethesda, Md.) - 23 Oct 2014

Smallwood Tangi L, Gatti Daniel M, Quizon Pamela, Weinstock George M, Jung Kuo-Chen, Zhao Liyang, Hua Kunjie, Pomp Daniel, Bennett Brian J

Abstract excerpt

Inbred mice exhibit strain-specific variation in susceptibility to atherosclerosis and dyslipidemia that renders them useful in dissecting the genetic architecture of these complex diseases. Traditional quantitative trait locus (QTL) mapping studies using inbred strains often identify large genomic regions, containing many genes, due to limited recombination and/or sample size. This hampers candidate gene...

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Identifiers

PMID: 25344410
DOI: 10.1534/g3.114.014704
PMCID: PMC4267931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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