Article
P53-mutation in smears of oral squamous cell carcinoma.
Anticancer research - 1 Jan 2000
Friedrich R E, Giese M, Riethdorf S, Loning T
Abstract excerpt
The tumor suppressor gene p53 encodes for an important cell cycle regulatory protein. Loss of the protein's function is probably important for the development of a variety of malignant diseases, including oral cancer. Up to present knowledge, the mutations of the p53 gene are one of the most frequent genetic alterations detectable in human cancer. The aim of this study was to explore the capability of molecular...
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