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Article

Detection of p53 gene mutations in oral squamous cell carcinomas of a black African population sample.

Human mutation - 1 Jan 1998

van Rensburg E J, Engelbrecht S, van Heerden W F, Kotze M J, Raubenheimer E J

Abstract excerpt

Mutations in the p53 gene have been reported in head and neck carcinomas. We determined the p53 mutation profile in 55 oral squamous cell carcinomas (OSCCs) from a black African population sample. DNA from all the patients were investigated using PCR amplification of the p53 gene (exons 5-9), followed by heteroduplex single-stranded conformational polymorphism (HEX-SSCP) analysis on the PCR products. Direct...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9450901
DOI: 10.1002/(SICI)1098-1004(1998)11:1<39::AID-HUMU6>3.0.CO;2-G

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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