Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1.

The Journal of biological chemistry - 26 Mar 2004

Dohke Yoko, Oh Young S, Ambudkar Indu S, Turner R James

Abstract excerpt

The TRPC ion channels are candidates for the store-operated Ca(2+) entry pathway activated in response to depletion of intracellular Ca(2+) stores. Hydropathy analyses indicate that these proteins contain eight hydrophobic regions (HRs) that could potentially form alpha-helical membrane-spanning segments. Based on limited sequence similarities to other ion channels, it has been proposed that only six of the eight...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acids
Share to Calcium Channels
Share to Cytosol

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endoplasmic Reticulum

Share to Glycosylation

Share to Luminescent Proteins

Share to TRPC Cation Channels

Source

Identifiers

PMID: 14707123
DOI: 10.1074/jbc.M312456200

Genes

TRPC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1.PMID 14707123Read ↗

TRPC1.Semantic proximity Read ↗

Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.Semantic proximity Read ↗

Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.Semantic proximity Read ↗

Structure of the receptor-activated human TRPC6 ion channelSemantic proximity Read ↗

The TRP channel superfamily: insights into how structure, protein-lipid interactions and localization influence function.Semantic proximity Read ↗

A structural requirement for processing the cardiac K+ channel KCNQ1.Semantic proximity Read ↗

Post-Translational Modification and Natural Mutation of TRPC Channels.Semantic proximity Read ↗

Coiled coils direct assembly of a cold-activated TRP channel.Semantic proximity Read ↗

Transmembrane topology of a CLC chloride channel.Semantic proximity Read ↗

TRPC3: a multifunctional signaling molecule.Semantic proximity Read ↗

Constitutive Inhibition of Transient Receptor Potential Canonical Type 6 (TRPC6) by O-GlcNAcylation at Threonine-221Semantic proximity Read ↗

Structural domains required for channel function of the mouse transient receptor potential protein homologue TRP1beta.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.