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Article

Coiled coils direct assembly of a cold-activated TRP channel.

Neuron - 20 Jul 2006

Tsuruda Pamela R, Julius David, Minor Daniel L

Abstract excerpt

Transient receptor potential (TRP) channels mediate numerous sensory transduction processes and are thought to function as tetramers. TRP channel physiology is well studied; however, comparatively little is understood regarding TRP channel assembly. Here, we identify an autonomously folded assembly domain from the cold- and menthol-gated channel TRPM8. We show that the TRPM8 cytoplasmic C-terminal domain contains...

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Source

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Identifiers

PMID: 16846855
DOI: 10.1016/j.neuron.2006.06.023
PMCID: PMC3014052

Genes

TRPM8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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