TRPC1.

Abstract excerpt

The TRPC1 ion channel was the first mammalian TRP channel to be cloned. In humans, it is encoded by the TRPC1 gene located in chromosome 3. The protein is predicted to consist of six transmembrane segments with the N- and C-termini located in the cytoplasm. The extracellular loop connecting transmembrane segments 5 and 6 participates in the formation of the ionic pore region. Inside the cell, TRPC1 is present in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Membrane Permeability
• Share to Gene Expression Regulation
• Share to Ion Channel Gating