Article
Structural domains required for channel function of the mouse transient receptor potential protein homologue TRP1beta.
FEBS letters - 17 Jul 2002
Engelke Michael, Friedrich Olaf, Budde Petra, Schäfer Christina, Niemann Ursula, Zitt Christof, Jüngling Eberhard, Rocks Oliver, Lückhoff Andreas, Frey Jürgen
Abstract excerpt
Transient receptor potential proteins (TRP) are supposed to participate in the formation of store-operated Ca(2+) influx channels by co-assembly. However, little is known which domains facilitate the interaction of subunits. Contribution of the N-terminal coiled-coil domain and ankyrin-like repeats and the putative pore region of the mouse TRP1beta (mTRP1beta) variant to the formation of functional cation...
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