Article
Detection and mapping of quantitative trait loci that determine responsiveness of mice to nitrous oxide antinociception.
Neuroscience - 1 Jan 2004
Mueller J L, Ellenberger E A, Vaughn L K, Belknap J K, Quock R M
Abstract excerpt
Exposure to 70% N(2)O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N(2)O. Offspring from the F(2) generation bred from B6 and D2 progenitors exhibited a broad range of responsiveness to N(2)O antinociception as determined by the acetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
