Article
Identification of an acute ethanol response quantitative trait locus on mouse chromosome 2.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jan 1999
Demarest K, McCaughran J, Mahjubi E, Cipp L, Hitzemann R
Abstract excerpt
A two-stage strategy was used to identify and confirm quantitative trait loci (QTLs) associated with the changes in locomotor activity induced by a 1.5 gm/kg ethanol challenge. For stage 1, putative QTLs were identified by analysis of the strain means for 25 strains of the BXD recombinant inbred (RI) series (males only). QTLs were identified on chromosomes 1, 2, 4, and 6. The activity response to chlordiazepoxide...
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