Article
Identification of an acute ethanol response quantitative trait locus on mouse chromosome 2.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jan 1999
Demarest K, McCaughran J, Mahjubi E, Cipp L, Hitzemann R
Abstract excerpt
A two-stage strategy was used to identify and confirm quantitative trait loci (QTLs) associated with the changes in locomotor activity induced by a 1.5 gm/kg ethanol challenge. For stage 1, putative QTLs were identified by analysis of the strain means for 25 strains of the BXD recombinant inbred...
Topics
- Animals
- Anti-Anxiety Agents
- Chlordiazepoxide
- Chromosome Mapping
- Chromosomes
- DNA
- Ethanol
- Female
- Genotype
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Microsatellite Repeats
- Motor Activity
- Quantitative Trait, Heritable
