Article
Identification of quantitative trait loci for locomotor activation and anxiety using closely related inbred strains.
Genes, brain, and behavior - 1 Oct 2008
Bailey J S, Grabowski-Boase L, Steffy B M, Wiltshire T, Churchill G A, Tarantino L M
Abstract excerpt
We carried out a quantitative trait loci (QTL) mapping experiment in two phenotypically similar inbred mouse strains, C57BL/6J and C58/J, using the open-field assay, a well-established model of anxiety-related behavior in rodents. This intercross was initially carried out as a control cross for an ethylnitrosurea mutagenesis mapping study. Surprisingly, although open-field behavior is similar in the two strains,...
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