Article
Genetics of ethanol-induced locomotor activation: detection of QTLs in a C57BL/6J x DBA/2J F2 intercross.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 1998
Hitzemann R, Cipp L, Demarest K, Mahjubi E, McCaughran J
Abstract excerpt
Moderate doses of ethanol (1-2 g/kg) markedly increase locomotor activity in some inbred mouse strains, for example, the DBA/2J (D2), but have relatively little effect in other strains, for example, the C57BL/6J (B6). In the present study, we conducted a genome-wide search in a B6D2 F2 intercross...
Topics
- Animals
- Chromosome Mapping
- Chromosomes
- Crosses, Genetic
- Ethanol
- Female
- Lod Score
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Microsatellite Repeats
- Motor Activity
- Phenotype
- Quantitative Trait, Heritable