Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics of ethanol-induced locomotor activation: detection of QTLs in a C57BL/6J x DBA/2J F2 intercross.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 1998

Hitzemann R, Cipp L, Demarest K, Mahjubi E, McCaughran J

Abstract excerpt

Moderate doses of ethanol (1-2 g/kg) markedly increase locomotor activity in some inbred mouse strains, for example, the DBA/2J (D2), but have relatively little effect in other strains, for example, the C57BL/6J (B6). In the present study, we conducted a genome-wide search in a B6D2 F2 intercross (N = 925) for quantitative trait loci (QTLs) associated with the locomotor response. A QTL with a LOD score of 8.4 was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Crosses, Genetic

Share to Lod Score

Share to Mice, Inbred C57BL

Share to Microsatellite Repeats

Share to Phenotype

Source

Identifiers

PMID: 9880659
DOI: 10.1007/s003359900906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics of ethanol-induced locomotor activation: detection of QTLs in a C57BL/6J x DBA/2J F2 intercross.PMID 9880659Read ↗

Further characterization and high-resolution mapping of quantitative trait loci for ethanol-induced locomotor activity.Semantic proximity Read ↗

Identification of an acute ethanol response quantitative trait locus on mouse chromosome 2.Semantic proximity Read ↗

Quantitative Trait Loci Involved in Genetic Predisposition to Acute Alcohol Withdrawal in MiceSemantic proximity Read ↗

Quantitative trait loci contributing to physiological and behavioural ethanol responses after acute and chronic treatment.Semantic proximity Read ↗

Genetic Variability in Adenosine Deaminase-Like Contributes to Variation in Alcohol Preference in Mice.Semantic proximity Read ↗

Genetic analysis of the psychomotor stimulant effect of ethanol.Semantic proximity Read ↗

Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanol-induced activation.Semantic proximity Read ↗

Identification of quantitative trait loci for locomotor activation and anxiety using closely related inbred strains.Semantic proximity Read ↗

Effects of acute and repeated ethanol exposures on the locomotor activity of BXD recombinant inbred mice.Semantic proximity Read ↗

Allelic variation in the GABA A receptor gamma2 subunit is associated with genetic susceptibility to ethanol-induced motor incoordination and hypothermia, conditioned taste aversion, and withdrawal in BXD/Ty recombinant inbred mice.Semantic proximity Read ↗

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.Semantic proximity Read ↗

Biometrical genetic analysis of ethanol's psychomotor stimulant effect.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.