Article
Quantitative trait loci for acute behavioral sensitivity to paraoxon.
Neurotoxicology and teratology - 1 Jan 2000
Risinger F O, Quick E, Belknap J K
Abstract excerpt
Genetic mechanisms responsible for organophosphate (OP)-induced behavioral changes remain obscure. In the present study, provisional quantitative trait loci (QTL) associated with acute sensitivity or insensitivity to hypolocomotion produced by the OP paraoxon were identified. Naive adult male and female mice of the BXD/Ty series (22 different BXD strains plus C57BL/6J and DBA/2J progenitor strains) received 0 or...
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