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Article

Cardiovascular and craniofacial defects in Crk-null mice.

Molecular and cellular biology - 1 Aug 2006

Park Tae-Ju, Boyd Kelli, Curran Tom

Abstract excerpt

The Crk adaptor protein, which is encoded by two splice variants termed CrkI and CrkII, contains both SH2 and SH3 domains but no catalytic region. It is thought to function in signal transduction processes involved in growth regulation, cell transformation, cell migration, and cell adhesion. Although the function of Crk has been studied in considerable detail in cell culture, its biological role in vivo is still...

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Identifiers

PMID: 16880535
DOI: 10.1128/MCB.00472-06
PMCID: PMC1592792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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