Article
The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins.
Nature genetics - 1 Mar 1996
Ebersole T A, Chen Q, Justice M J, Artzt K
Abstract excerpt
The mouse quaking gene, essential for nervous system myelination and survival of the early embryo has been positionally cloned. Its sequence implies that the locus encodes a multifunctional gene used in a specific set of developing tissues to unite signal transduction with some aspect of RNA metabolism. The quaking(viable) (qkv) mutation has one class of messages truncated by a deletion. An independent...
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