Article
The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins.
Nature genetics - 1 Mar 1996
Ebersole T A, Chen Q, Justice M J, Artzt K
Abstract excerpt
The mouse quaking gene, essential for nervous system myelination and survival of the early embryo has been positionally cloned. Its sequence implies that the locus encodes a multifunctional gene used in a specific set of developing tissues to unite signal transduction with some aspect of RNA meta...
Topics
- Adaptor Proteins, Signal Transducing
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Cloning, Molecular
- DNA Primers
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Humans
- Mice
- Mice, Inbred DBA
