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Article

Mutational analysis of susceptibility genes RNASEL/HPC1, ELAC2/HPC2, and MSR1 in sporadic prostate cancer.

Genes, chromosomes & cancer - 1 Feb 2004

Nupponen Nina N, Wallén Mika J, Ponciano Damaris, Robbins Christiane M, Tammela Teuvo L J, Vessella Robert L, Carpten John D, Visakorpi Tapio

Abstract excerpt

Three putative prostate cancer-susceptibility genes, RNASEL/HPC1 at 1q24, MSR1 at 8p22, and ELAC2/HPC2 at 17p11, have recently been identified. Our objective was to investigate somatic mutations in these genes in sporadic prostate cancer. We analyzed 39 clinical prostate cancer specimens, 10 prostate cancer xenografts (LuCaP series), and 4 prostate cancer cell lines (LNCaP, DU145, PC-3, and MPC-3) for genetic...

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Source

Identifiers

PMID: 14695991
DOI: 10.1002/gcc.10308

Genes

RNASEL
ELAC2
MSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutational analysis of susceptibility genes RNASEL/HPC1, ELAC2/HPC2, and MSR1 in sporadic prostate cancer.PMID 14695991Read ↗

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