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Article

Analysis of the RNASEL gene in familial and sporadic prostate cancer.

American journal of human genetics - 1 Jul 2002

Wang Liang, McDonnell Shannon K, Elkins David A, Slager Susan L, Christensen Eric, Marks Angela F, Cunningham Julie M, Peterson Brett J, Jacobsen Steven J, Cerhan James R, Blute Michael L, Schaid Daniel J, Thibodeau Stephen N

Abstract excerpt

The RNASEL gene on chromosome 1q25 was recently identified as a candidate gene for hereditary prostate cancer (PC). To confirm these findings, we screened 326 patients from 163 families with familial PC for potential germline mutations, by use of conformation-sensitive gel electrophoresis, followed by direct sequence analysis. A total of six variants were identified, including one intronic and five exonic changes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12022038
DOI: 10.1086/341281
PMCID: PMC384968

Genes

RNASEL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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