Article
HPC2/ELAC2 polymorphism associated with Japanese sporadic prostate cancer.
The Prostate - 1 Nov 2004
Yokomizo Akira, Koga Hirofumi, Kinukawa Naoko, Tsukamoto Taiji, Hirao Yoshihiko, Akaza Hideyuki, Mori Mitsuru, Naito Seiji
Abstract excerpt
BACKGROUND: HPC2/ELAC2 gene was identified by linkage analysis from familial prostate cancer (Pca) patients in USA. To determine the association of HPC2/ELAC2 gene with Japanese sporadic Pca, we performed a case-control study focused on two missense polymorphisms. METHODS: We genotyped the two polymorphic sites of Ser217Leu and Ala541Thr in sporadic Japanese Pca patients (n = 285) and matched controls (n = 233)....
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