Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of HPC2/ELAC2 and RNASEL non-synonymous variants with prostate cancer risk in African American familial and sporadic cases.

The Prostate - 1 Dec 2008

Robbins Christiane M, Hernandez Wenndy, Ahaghotu Chiledum, Bennett James, Hoke Gerald, Mason Terry, Pettaway Curtis A, Vijayakumar Srinivasan, Weinrich Sally, Furbert-Harris Paulette, Dunston Georgia, Powell Isaac J, Carpten John D, Kittles Rick A

Abstract excerpt

INTRODUCTION: The RNASEL and HPC2/ELAC2 genes have been implicated in hereditary prostate cancer. Further assessment of the role of these genes in sporadic prostate cancer in African American men (AAM) is warranted. METHODS: Genotyping of HPC2/ELAC2 variants (S217L, A541T), along with RNASEL variants (R462Q and E541D) was completed in 155 African American sporadic and 88 familial prostate cancer cases, and 296...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Endoribonucleases

Share to Haplotypes

Share to Logistic Models

Share to Neoplasm Proteins

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 18767027
DOI: 10.1002/pros.20841
PMCID: PMC4097307

Genes

RNASEL
ELAC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of HPC2/ELAC2 and RNASEL non-synonymous variants with prostate cancer risk in African American familial and sporadic cases.PMID 18767027Read ↗

Association of hereditary prostate cancer gene polymorphic variants with sporadic aggressive prostate carcinoma.Semantic proximity Read ↗

Single and multivariate associations of MSR1, ELAC2, and RNASEL with prostate cancer in an ethnic diverse cohort of men.Semantic proximity Read ↗

Association of HPC2/ELAC2 polymorphisms with risk of prostate cancer in a population-based study.Semantic proximity Read ↗

Evaluation of linkage and association of HPC2/ELAC2 in patients with familial or sporadic prostate cancer.Semantic proximity Read ↗

Polymorphisms in the prostate cancer susceptibility gene HPC2/ELAC2 in multiplex families and healthy controls.Semantic proximity Read ↗

Association of RNASEL variants with prostate cancer risk in Hispanic Caucasians and African Americans.Semantic proximity Read ↗

Mutational analysis of susceptibility genes RNASEL/HPC1, ELAC2/HPC2, and MSR1 in sporadic prostate cancer.Semantic proximity Read ↗

Genetic analysis of the RNASEL gene in hereditary, familial, and sporadic prostate cancer.Semantic proximity Read ↗

Association of susceptibility alleles in ELAC2/HPC2, RNASEL/HPC1, and MSR1 with prostate cancer severity in European American and African American men.Semantic proximity Read ↗

Perspective: prostate cancer susceptibility genes.Semantic proximity Read ↗

Association of HPC2/ELAC2 genotypes and prostate cancer.Semantic proximity Read ↗

ELAC2 polymorphisms and prostate cancer risk: a meta-analysis based on 18 case-control studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.