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Article

Association of selected ELAC2, MSR1, RNASEL and KLK3 polymorphisms with prostate cancer susceptibility in a Hungarian cohort.

Pathology oncology research : POR - 1 Jan 2026

Kovacs Sebestyen, Szalai Renata, Barati Laszlo, Hadzsiev Kinga

Abstract excerpt

Background: Prostate cancer (PCa) remains a leading malignancy among men worldwide, with inherited genetic susceptibility playing a pivotal role in its pathogenesis. Although numerous single nucleotide polymorphisms (SNPs) within immune response, inflammatory, and apoptotic pathways have been linked to PCa risk, these associations often exhibit substantial inconsistency across diverse populations. This study...

Read the complete abstract on PubMed

Topics

Humans
Male
Prostatic Neoplasms
Case-Control Studies
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Kallikreins

Aged

Prostate-Specific Antigen

Hungary

Middle Aged

Endoribonucleases

Biomarkers, Tumor

Prognosis

Cohort Studies

Genotype

Follow-Up Studies

Neoplasm Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 42729212
DOI: 10.3389/pore.2026.1612550
PMCID: PMC13561955

Genes

RNASEL
ELAC2
KLK3
MSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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