Article
Association of HPC2/ELAC2 polymorphisms with risk of prostate cancer in a population-based study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2003
Stanford Janet L, Sabacan Leah P, Noonan Elizabeth A, Iwasaki Lori, Shu Jianfen, Feng Ziding, Ostrander Elaine A
Abstract excerpt
Genetic polymorphism in HPC2/ELAC2 was recently associated with risk of sporadic prostate cancer. To determine the contribution of two HPC2/ELAC2 missense variants (Ser217Leu and Ala541Thr) to the risk of developing prostate cancer, we conducted a population-based case-control study of middle-aged men (40-64 years). Cases (n=591) were ascertained from the Seattle-Puget Sound Surveillance, Epidemiology, and End...
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