Article
Frequent loss of heterozygosity targeting the inactive X chromosome in melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2003
Indsto James O, Nassif Najah T, Kefford Richard F, Mann Graham J
Abstract excerpt
After previous preliminary observations of paradoxical deletion events affecting the inactive X chromosome in melanoma, we have surveyed the X chromosome for deletions using 23 polymorphic microsatellite markers in 28 informative (female XX) metastatic melanomas. Ten tumors (36%) showed at least...
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