Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent loss Xq25 on the inactive X chromosome in primary breast carcinomas is associated with tumor grade and axillary lymph node metastasis.

Genes, chromosomes & cancer - 1 Mar 2002

Piao Zhe, Malkhosyan Sergei R

Abstract excerpt

We previously applied arbitrarily primed polymerase chain reaction DNA fingerprinting to identify molecular genetic alterations in primary breast carcinomas. One of the most frequently observed fingerprint alterations was a reduction in the intensity of the MCG1-B2 band in 32% of tumors, indicating recurrent loss of X-chromosome segments. This article reports a mapping analysis of those chromosomal deletions. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Ductal, Breast
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Fingerprinting

Share to Dosage Compensation, Genetic

Share to Genes, Tumor Suppressor

Share to Loss of Heterozygosity

Share to Lymphatic Metastasis

Share to X Chromosome

Source

Identifiers

PMID: 11807983
DOI: 10.1002/gcc.10024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent loss Xq25 on the inactive X chromosome in primary breast carcinomas is associated with tumor grade and axillary lymph node metastasis.PMID 11807983Read ↗

Androgen receptor CAG repeats, non-random X chromosome inactivation, and loss of heterozygosity at Xq25 in relation to breast cancer risk.Semantic proximity Read ↗

Frequent loss of heterozygosity targeting the inactive X chromosome in melanoma.Semantic proximity Read ↗

Loss of heterozygosity on chromosome XP22.2-p22.13 and Xq26.1-q27.1 in human breast carcinomas.Semantic proximity Read ↗

A one centimorgan deletion unit on chromosome Xq12 is commonly lost in borderline and invasive epithelial ovarian tumors.Semantic proximity Read ↗

Allelic loss on chromosome 9q is associated with lymph node metastasis of primary breast cancer.Semantic proximity Read ↗

Mapping of a new target region of allelic loss to a 2-cM interval at 22q13.1 in primary breast cancer.Semantic proximity Read ↗

Loss of heterozygosity on the X chromosome in human breast cancer.Semantic proximity Read ↗

Significant allelic loss of ANX7region (10q21) in hormone receptor negative breast carcinomas.Semantic proximity Read ↗

Differential methylation of the hypervariable locus DXS255 on active and inactive X chromosomes correlates with the expression of a human X-linked gene.Semantic proximity Read ↗

The hypervariable DXS255 locus contains a LINE-1 repetitive element with a CpG island that is extensively methylated only on the active X chromosome.Semantic proximity Read ↗

Identification of novel deletion regions on chromosome arms 2q and 6p in breast carcinomas by amplotype analysisSemantic proximity Read ↗

Loss of heterozygosity on chromosome 11 q in breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.