Loss of heterozygosity on chromosome XP22.2-p22.13 and Xq26.1-q27.1 in human breast carcinomas.

doi:10.3346/jkms.1998.13.3.311

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Article

Loss of heterozygosity on chromosome XP22.2-p22.13 and Xq26.1-q27.1 in human breast carcinomas.

Journal of Korean medical science - 1 Jun 1998

Choi C, Kim M H, Juhng S W

Abstract excerpt

In an attempt to investigate the X chromosome harboring putative tumor suppressor genes (TSGs) in sporadic breast carcinoma, we performed loss of heterozygosity (LOH) studies on 23 breast carcinomas using 15 polymorphic markers covering the whole X chromosomes. Matched DNA extracted from tumor sa...

Topics

Adenocarcinoma
Adult
Alleles
Breast Neoplasms
DNA, Neoplasm
Female
Genes, Tumor Suppressor
Humans
Loss of Heterozygosity
Middle Aged
Polymorphism, Genetic
X Chromosome

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