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Article

Identification of two distinct deletion targets at 11q23 in cutaneous malignant melanoma.

International journal of cancer - 18 Jan 1999

Herbst R A, Gutzmer R, Matiaske F, Mommert S, Casper U, Kapp A, Weiss J

Abstract excerpt

Karyotypic and molecular data indicate that genetic alterations of the long arm of chromosome 11 (11q) are involved in the pathogenesis of malignant melanoma as well as of other malignancies. We have shown previously, by analysis of loss of heterozygosity (LOH), that a tumor-suppressor gene playing an important role in malignant melanoma is likely to be located within a 51-cM region at 11q23. Its loss appeared to...

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Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 9935201
DOI: 10.1002/(sici)1097-0215(19990118)80:2<205::aid-ijc8>3.0.co;2-j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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