Article
Glucocorticoids promote development of the osteoblast phenotype by selectively modulating expression of cell growth and differentiation associated genes.
Journal of cellular biochemistry - 1 Dec 1992
Shalhoub V, Conlon D, Tassinari M, Quinn C, Partridge N, Stein G S, Lian J B
Abstract excerpt
To understand the mechanisms by which glucocorticoids promote differentiation of fetal rat calvaria derived osteoblasts to produce bone-like mineralized nodules in vitro, a panel of osteoblast growth and differentiation related genes that characterize development of the osteoblast phenotype has been quantitated in glucocorticoid-treated cultures. We compared the mRNA levels of osteoblast expressed genes in...
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