Article
Expression of cell growth and bone specific genes at single cell resolution during development of bone tissue-like organization in primary osteoblast cultures.
Journal of cellular biochemistry - 1 Jul 1992
Pockwinse S M, Wilming L G, Conlon D M, Stein G S, Lian J B
Abstract excerpt
Primary cultures of calvarial derived normal diploid osteoblasts undergo a developmental expression of genes reflecting growth, extracellular matrix maturation, and mineralization during development of multilayered nodules having a bone tissue-like organization. Scanning electron microscopy of th...
Topics
- Animals
- Cell Division
- Cells, Cultured
- Diploidy
- Gene Expression
- Kinetics
- Microscopy, Electron
- Microscopy, Electron, Scanning
- Nucleic Acid Hybridization
- Osteoblasts
- Osteogenesis
- Osteosarcoma
- Phenotype
- Rats
- Tumor Cells, Cultured