Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hormonal regulation of the osteoblastic phenotype expression in neonatal murine calvarial cells.

Calcified tissue international - 1 Apr 1999

Chen T L, Fry D

Abstract excerpt

Osteoblastic cell cultures from fetal rat calvariae have provided a popular model for studying the effects of dexamethasone (DEX) and 1, 25 dihydroxyvitamin D3 [1,25(OH)2D3] on gene expression but data from murine calvarial cells are scarce. Species-specific responses of rat and mouse osteoblastic cells to these hormones have been reported previously. In the present study, we investigated the effects of DEX and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alkaline Phosphatase
Share to Dexamethasone
Share to Glucocorticoids

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Osteoblasts

Share to Osteocalcin

Share to Osteogenesis

Share to Vitamin D

Source

Identifiers

PMID: 10089223
DOI: 10.1007/s002239900624

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hormonal regulation of the osteoblastic phenotype expression in neonatal murine calvarial cells.PMID 10089223Read ↗

Glucocorticoids promote development of the osteoblast phenotype by selectively modulating expression of cell growth and differentiation associated genes.Semantic proximity Read ↗

Changes in osteoblast phenotype during differentiation of enzymatically isolated rat calvaria cells.Semantic proximity Read ↗

The developmental stages of osteoblast growth and differentiation exhibit selective responses of genes to growth factors (TGF beta 1) and hormones (vitamin D and glucocorticoids).Semantic proximity Read ↗

Age-related changes in bone formation, osteoblastic cell proliferation, and differentiation during postnatal osteogenesis in human calvaria.Semantic proximity Read ↗

Developmental stage-specific cellular responses to vitamin D and glucocorticoids during differentiation of the osteoblast phenotype: interrelationship of morphology and gene expression by in situ hybridization.Semantic proximity Read ↗

Phenotypic effects of continuous or discontinuous treatment with dexamethasone and/or calcitriol on osteoblasts differentiated from rat bone marrow stromal cells.Semantic proximity Read ↗

Triiodothyronine (T3) and 1,25-dihydroxyvitamin D3 (1,25D3) inversely regulate OPG gene expression in dependence of the osteoblastic phenotype.Semantic proximity Read ↗

Effects of bone morphogenetic protein-2 on human neonatal calvaria cell differentiation.Semantic proximity Read ↗

Genomic Determinants of Gene Regulation by 1,25-Dihydroxyvitamin D3 during Osteoblast-lineage Cell DifferentiationSemantic proximity Read ↗

Multiple levels of steroid hormone-dependent control of osteocalcin during osteoblast differentiation: glucocorticoid regulation of basal and vitamin D stimulated gene expression.Semantic proximity Read ↗

The response to sex steroid hormones and vitamin D of cultured osteoblasts derived from ovariectomized mice with and without 17beta-estradiol pretreatment.Semantic proximity Read ↗

Osteoblast lineage-specific effects of notch activation in the skeleton.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.