Article
[Studies on the reduction of malignant phenotypes in a highly metastatic human lung carcinoma--correlated changes of intercellular communication, cytoskeletons, oncogenes and antioncogene].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Mar 1994
Zhang Z Q, Lin Z X, Lu Y Y
Abstract excerpt
Human lung giant cell carcinoma cell line PG is characterized by its highly metastatic (100%) behavior in nude mice. When compared with cultured normal human fetal lung cells, PG cells were deficient in gap junctional intercellular communication (GJIC) function as detected by Scrape Loading and D...
Topics
- Animals
- Calmodulin
- Carcinoma, Giant Cell
- Cell Communication
- Cell Division
- Cytoskeleton
- Drugs, Chinese Herbal
- Gene Amplification
- Genes, myc
- Genes, p53
- Genes, ras
- Humans
- Imidazoles
- Lung Neoplasms
- Mice
- Mice, Nude
- Phenotype
- Tumor Cells, Cultured