Article
[Inhibition effect of p53 antisense RNA on malignant phenotype of colorectal cancer cells].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Mar 1997
Cao J, Teng L, Cai X
Abstract excerpt
OBJECTIVE: Inhibition effect of p53 antisense RNA on malignant phenotype of colorectal cancer cells was studied. METHODS: For the purpose of inhibiting tumorigenecity of mutant p53 gene in colorectal cancer cells, a 2.1 kb human p53 full length cDNA was inserted into a mammalian expression vector pREP9 to make a p53 antisense RNA expression vector pREP9-p53 (AS). pREP9-p53 (AS) was then introduced into human...
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