Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational robustness of 16S ribosomal RNA, shown by experimental horizontal gene transfer in Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America - 20 Nov 2012

Kitahara Kei, Yasutake Yoshiaki, Miyazaki Kentaro

Abstract excerpt

The bacterial ribosome consists of three rRNA molecules and 57 proteins and plays a crucial role in translating mRNA-encoded information into proteins. Because of the ribosome's structural and mechanistic complexity, it is believed that each ribosomal component coevolves to maintain its function. Unlike 5S rRNA, 16S and 23S rRNAs appear to lack mutational robustness, because they form the structural core of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Transfer, Horizontal
Share to Gene Transfer Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Bacterial

Share to Nucleic Acid Conformation

Share to Nucleotides

Share to Ribosomal Proteins

Share to RNA, Bacterial

Share to RNA, Ribosomal, 16S

Source

Open in PubMed Open full text

Identifiers

PMID: 23112186
DOI: 10.1073/pnas.1213609109
PMCID: PMC3511107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational robustness of 16S ribosomal RNA, shown by experimental horizontal gene transfer in Escherichia coli.PMID 23112186Read ↗

Ribosomal RNAs are tolerant toward genetic insertions: evolutionary origin of the expansion segments.Semantic proximity Read ↗

Large variations in bacterial ribosomal RNA genes.Semantic proximity Read ↗

Rapid in vivo exploration of a 5S rRNA neutral network.Semantic proximity Read ↗

Directed evolution of rRNA improves translation kinetics and recombinant protein yield.Semantic proximity Read ↗

Saturation mutagenesis of 5S rRNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genetic evidence against the 16S ribosomal RNA helix 27 conformational switch model.Semantic proximity Read ↗

Functional analysis of the invariant residue G791 of Escherichia coli 16S rRNA.Semantic proximity Read ↗

Quantitative analysis of horizontal gene transfer in complex systems.Semantic proximity Read ↗

Phenotypic and genetic barriers to establishment of horizontally transferred genes encoding ribosomal protection proteins.Semantic proximity Read ↗

Structural adaptations for enhanced translation kinetics in evolved ribosomes.Semantic proximity Read ↗

Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly.Semantic proximity Read ↗

Functional genetic selection of Helix 66 in Escherichia coli 23S rRNA identified the eukaryotic-binding sequence for ribosomal protein L2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.