Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations in ribosomal protein L19 that decrease the fidelity of translation.

Biochimie - 1 Jan 2000

VanNice John, Gregory Steven T, Kamath Divya, O'Connor Michael

Abstract excerpt

Ribosomal protein L19 is an essential ribosomal protein and is a component of bridge B8, one of the protein-RNA bridges linking the large and small ribosomal subunits. Bridge B8 also contributes to the accuracy of translation by affecting GTPase activation by ribosome-bound aminoacyl tRNA-EF-Tu•GTP ternary complexes. Previous work has identified a limited number of accuracy-altering alterations in protein L19 of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA, Transfer, Amino Acyl
Share to Guanosine Triphosphate
Share to Nucleic Acid Conformation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Peptide Elongation Factor Tu

Share to Protein Biosynthesis

Share to Protein Domains

Share to Ribosomal Proteins

Share to RNA, Ribosomal, 16S

Source

Open in PubMed Open full text

Identifiers

PMID: 27477481
DOI: 10.1016/j.biochi.2016.07.015
PMCID: PMC5859582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations in ribosomal protein L19 that decrease the fidelity of translation.PMID 27477481Read ↗

Error-prone and error-restrictive mutations affecting ribosomal protein S12.Semantic proximity Read ↗

rRNA modifications in an intersubunit bridge of the ribosome strongly affect both ribosome biogenesis and activity.Semantic proximity Read ↗

Mutations in the intersubunit bridge regions of 16S rRNA affect decoding and subunit-subunit interactions on the 70S ribosome.Semantic proximity Read ↗

Alterations in the ribosomal protein bL12 of E. coli affecting the initiation, elongation and termination of protein synthesis.Semantic proximity Read ↗

Distinct functional classes of ram mutations in 16S rRNA.Semantic proximity Read ↗

Analysis of the function of E. coli 23S rRNA helix-loop 69 by mutagenesis.Semantic proximity Read ↗

A mutation at the universally conserved position 529 in Escherichia coli 16S rRNA creates a functional but highly error prone ribosome.Semantic proximity Read ↗

Functional genetic selection of Helix 66 in Escherichia coli 23S rRNA identified the eukaryotic-binding sequence for ribosomal protein L2.Semantic proximity Read ↗

Multiple defects in translation associated with altered ribosomal protein L4.Semantic proximity Read ↗

Hyperaccurate and error-prone ribosomes exploit distinct mechanisms during tRNA selection.Semantic proximity Read ↗

A novel single amino acid change in small subunit ribosomal protein S5 has profound effects on translational fidelity.Semantic proximity Read ↗

Mutations in conserved helix 69 of 23S rRNA of Thermus thermophilus that affect capreomycin resistance but not posttranscriptional modifications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.